Dr. Johannes Coy on His Metabolic Approach to Cancer

Dec 10, 2025 | Insights, News

Dr. Johannes Coy has uncovered a biological master key: the TKTL1 gene, a molecular switch that governs how cells grow, repair, and protect themselves. His discovery reveals a remarkable dual mechanism. TKTL1 acts like the body’s “scissors,” cutting sugar into vital building blocks for new cells, while at the same time creating a protective lactic-acid shield. In healthy development, this shield protects the embryo; in disease, cancer cells and pathogens exploit it to hide from the immune system.

Building on this insight, Dr. Coy has developed a strategy to “block the scissors,” inhibiting TKTL1 in order to disrupt the survival tactics of cancer cells, viruses, bacteria, and malaria pathogens. This breakthrough opens up three revolutionary fields of application: improving cancer and infectious disease therapies, enabling ultra-early tumour detection through a blood test, and creating health-promoting nutrition that allows people to enjoy foods with smart sugars that stabilise blood sugar and support wellbeing. RMDM’s One Stop Shop approach focuses on the core of TKTL1 activity and translates this science into practical solutions that help people prevent and manage disease more effectively.

Read the full interview here.